Clinical Trials

Fast Facts

Our clinical trials portfolio includes:

  • More than 40 research studies
  • More than 10 Pediatric-focused studies
  • Five phase-1 Trials
  • First-In-Human treatments
  • Investigational New Drugs developed at UF

Featured Trial

BRAVO

Patients in this study will either receive concurrent TMZ during RT and immunotherapy during and after maintenance cycles of dose-intensive TMZ (Group A) or focal radiotherapy alone and immunotherapy without maintenance DI TMZ (Group B). Immune responses during cycles of DC vaccination with or without DI TMZ will be evaluated in both treatment groups.

Subject inclusion criteria:

  • Age: 3 to 21 years old
  • Radiologically confirmed DIPG and patient and/or parents/guardian willing to consent to biopsy
  • performance status
  • Bone Marrow, Renal and Hepatic tests

Read more about the BRAVO Clinical Trial

Contact Marcia Hodik to hear more about the BRAVO Clinical Trial.

 


Browse or search current neurosurgery clinical trials

PNOC 013

A Safety and Pharmacokinetic Study of Single Agent REGN2810 in Pediatric Patients with Relapsed or Refractory Solid or Central Nervous System (CNS) Tumors and a Safety and Efficacy Trial of REGN2810 in Combination with Radiotherapy in Pediatric Patients with Newly Diagnosed Diffuse Intrinsic Pontine Glioma, Newly Diagnosed High-Grade Glioma, or Recurrent High-Grade Glioma

Adult or Pediatric?

Both

Type of Study
  • Randomized
  • Drug
  • Treatment
  • Interventional
Disease

Central Nervous System Tumor

Disease Type

DIPG
Newly diagnosed high-grade glioma
Recurrent high-grade glioma