Clinical Trials

Fast Facts

Our clinical trials portfolio includes:

  • More than 40 research studies
  • More than 10 Pediatric-focused studies
  • Five phase-1 Trials
  • First-In-Human treatments
  • Investigational New Drugs developed at UF

Featured Trial

PNOC 020

A Phase I/II Study of RNA-lipid particle (RNA-LP) vaccines for Newly Diagnosed Pediatric High-Grade Gliomas (pHGG) and Adult Glioblastoma (GBM).

Subject inclusion criteria:

  • Age: 21 Years and older (Adult, Older Adult)
  • Histopathologically proven newly-diagnosed de novo GBM (WHO Grade IV glioma) (secondary GBM not eligible) that is MGMT unmethylated.
  • The tumor must have a supratentorial component.
  • Bone Marrow, Renal and Hepatic tests

See full inclusion criteria and learn more about the PNOC 020 Clinical Trial

Contact Marcia Hodik to hear more about the PNOC 020 Clinical Trial.

 


Browse or search current neurosurgery clinical trials

HeadStart 4

Newly Diagnosed Children (Less than 10 Years Old) With Medulloblastoma and Other Central Nervous System Primitive Neuro-Ectodermal Tumors: Clinical and Molecular Risk-Tailored Intensive and Compressed Induction Chemotherapy Followed by Consolidation with Either Single-Cycle (Low Risk Patients) or Randomization (High Risk Patients) to either Single-Cycle or to Three Tandem Cycles of Marrow-Ablative Chemotherapy with Autologous Hematopoietic Progenitor Cell Rescue

Adult or Pediatric?

Pediatric

Type of Study
  • Randomized
Disease

Brain Tumor

Disease Type

Medulloblastoma
Central Nervous System Embryonal Tumors

Drug

Induction

Drug Type

Chemotherapy