Clinical Trials

Fast Facts

Our clinical trials portfolio includes:

  • More than 40 research studies
  • More than 10 Pediatric-focused studies
  • Five phase-1 Trials
  • First-In-Human treatments
  • Investigational New Drugs developed at UF

Pediatric Clinical Trials

Featured Trial

BRAVO

Patients in this study will either receive concurrent TMZ during RT and immunotherapy during and after maintenance cycles of dose-intensive TMZ (Group A) or focal radiotherapy alone and immunotherapy without maintenance DI TMZ (Group B). Immune responses during cycles of DC vaccination with or without DI TMZ will be evaluated in both treatment groups.

Subject inclusion criteria:

  • Age: 3 to 21 years old
  • Radiologically confirmed DIPG and patient and/or parents/guardian willing to consent to biopsy
  • performance status
  • Bone Marrow, Renal and Hepatic tests

Read more about the BRAVO Clinical Trial

Contact Marcia Hodik to hear more about the BRAVO Clinical Trial.

 


Browse or search current neurosurgery clinical trials

HeadStart 4

Newly Diagnosed Children (Less than 10 Years Old) With Medulloblastoma and Other Central Nervous System Primitive Neuro-Ectodermal Tumors: Clinical and Molecular Risk-Tailored Intensive and Compressed Induction Chemotherapy Followed by Consolidation with Either Single-Cycle (Low Risk Patients) or Randomization (High Risk Patients) to either Single-Cycle or to Three Tandem Cycles of Marrow-Ablative Chemotherapy with Autologous Hematopoietic Progenitor Cell Rescue

Adult or Pediatric?

Pediatric

Type of Study
  • Randomized
Disease

Brain Tumor

Disease Type

Medulloblastoma
Central Nervous System Embryonal Tumors

Drug

Induction

Drug Type

Chemotherapy

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