Loic P. Deleyrolle, PhD

Loic P. Deleyrolle, Ph.D.

Special Interests

  • Glioma
  • Tumor initiating Cells
  • Innovative Technologies
  • Neural Stem Cell Functions and Dysfunctions


Loic P. Deleyrolle received his PhD degree in Neurobiology in 2006 from the University of Montpellier (France), where he studied the molecular pathways regulating proliferation and differentiation of spinal cord stem, and progenitor cells. He then joined Dr. Brent Reynolds’ laboratory as a postdoctoral research associate at the Queensland Brain Institute of the University of Queensland (Australia) until 2008, and subsequently moved with the lab to the McKnight Brain Institute at the University of Florida.

Dr. Deleyrolle’s current research is focused on investigating the key cellular, molecular and genetic mechanisms underlying brain tumor heterogeneity, evolvability, and therapy resistance. His approaches to understanding the problem are diverse, and include the development and use of innovative technologies to identify and measure cancer stem cell activity. Through exploring novel treatment strategies via drug screening, Dr. Deleyrolle hopes to uncover new translational therapeutic paradigms. His current research also investigates the role of somatic neural stem cells in the regulation of energy metabolism and food behavior.