David D. Tran, MD, PhD

Dr. David Tran smiling in his lab

Appointments: (352) 273-9000

Special Interests

  • Novel Therapies for Brain Cancer
  • Neuro-Oncology
  • Mesenchymal Factors in Gliomagenesis
  • Molecular Mechanism of Cancer Cell Migration
  • Regulation of the Epithelial-Mesenchymal Transition and Tumor Dormancy
  • Brain Metastasis
  • Cancer Genomics


David Tran, MD, PhD, joined the University of Florida faculty in the spring of 2015. Prior to his arrival, he was the director of the adult neuro-oncology section in the oncology division and an assistant professor in the Department of Medicine at Washington University in St. Louis, Missouri.

In 1996, Dr. Tran received a bachelor’s degree in biochemistry from the University of Washington in Seattle. By 2005, he also had obtained a medical degree and a PhD in immunology from Mayo Medical School in Rochester, Minn. Dr. Tran is board certified in internal medicine and medical oncology. He is a member of the American Medical Association, the American Society of Clinical Oncology and the Society for Neuro-Oncology.

Medical Licensure and Board Certification

  • 2005 Medical License, Missouri 2007008871
  • 2008-2018 Board Certification in Internal Medicine
  • 2012-2022 Board Certification In Medical Oncology


  • Physician Scientist Training Program Scholarship
  • Washington University School of Medicine
  • Mallinckrodt Foundation Post-doctoral Research
  • Fellowship in Medical Oncology
  • Concept Award, Department of Defense
  • Young Investigator Award, Conquer Cancer Foundation
  • ASCO
  • Cancer Frontier Fund Award, BJH Foundation
  • Pardee Foundation Scholar Award

Recent Journal Articles

Impact of lp/1 9g codeletion and histology on outcomes of anaolastic gliomas treated with radiation therapy and temozolomide.

Speirs CK. Simpson JR. Robinson CG. DeWees TA. Tran DD. Linette G. Chicoine MR. Dacey RG.
Rich KM. Dovviing JL. Leuthardt EC. Zipfel GJ. Kim AH. Huang J.
lntJ RadiatOncol Biol Phys. 2015 Feb 1;91(2):268-76. dol: 10.10161j.ijrobp.2014.10.027.
PMID: 25636755

Stereotactic laser ablation on high-grade gliomas

Hawasli AH. Kim AH. Dunn GP, Tran DD. Leuthardt EC.
Neurosurg Focus. 2014 Dec:37(6):E1. dol: 10.31711201 4.9.FOCUS1 4471.
PMID: 25434378

Central nervous system cancers. version 22014. Featured updates to the NCCN Guidelines.

Nabors LB. Portnow J. Ammirati M. Brem H. Brown P. Butowski N. Chamberlain MC. DeAngelis LM.
Fenstermaker RA. Friedman A. Gilbert MR. Hattangadi-Gluth J. Hesser D. Holdhoff M. Junck L.
Lawson R. Loeffler JS. Moots PL. Mrugala MM. Newton HB. Raizer JJ. Recht L. Shonka N. Shrieve
DC. Sills AK Jr, Swinnen U. Tran D. Tran N. Vrionis FD. Wen PY. McMillian NR. Ho M.
J NatI ComprCanc Netw. 2014 Nov;12(11):1517-23.
PMID: 25361798 Free PMC Article

Radiation therapy dose escalation for glioblastoma multiforme in the era of temozolomide

Badiyan SN. Markovina S, Simpson JR. Robinson CG. DeWees T. Tran DD. Linette G. Jalalizadeh
R. Dacey R. Rich KM. Chicoine MR. Dowling JL. Leuthardt EC. Zipfel GJ, Kim AH. Huang J.
lntJ RadiatOncol Biol Phys. 2014 Nov 15;90(4):877-85. dol: 10.10161j.ijrobp.2014.07.014. Epub 2014 Sep 23.
PMID: 25257812

Transient SNAIL1 expression is necessary for metastatic competence in breast cancer

Tran HD. Luitel K. Kim M. Zhang K. Longmore GD. Tran DD.
Cancer Res. 2014 Nov 174(21 ):6330-40. doi: 10.11 58/0008-5472.CAN-14-0923. Epub 2014 Aug 27.
PMID: 25164016

Review all Dr. Tran’s Articles and Publications

Research Profile

My research program is focused understanding the mechanism of cancer metastasis and dormancy. The epithelial mesenchymal transition (EMT) is now suggested to play an important role in the initial invasion during cancer metastasis. However, direct in vivo evidence is currently lacking.

Our lab is interested in understanding how cancer EMT contributes to cancer metastasis, and if so whether it also regulates cancer dormancy, a phenomenon in which micrometastatic disease is present in multiple organs but clinically undetectable.

Visit the Translational Lab page for more.

Professional Appointments

  • Assistant Professor of Medicine, Tenure Track
    Molecular Oncology
    Washington University School of Medicine
    St. Louis, MO
  • Attending Physician
    Barnes Jewish Hospital and Siteman Cancer Center
    St. Louis, MO
  • Attending Physician
    Barnes Jewish West County Hospital
    St. Louis, MO

Honors and Awards

  • 1992-1996 University and College Dean’s List, 1992-1996
  • 1994-1997 Honor Undergraduate Research Scholar, the University of Washington and the Bristol-Myers Squibb Pharmaceutical Research Institute, Seattle, WA
  • 1996 The University of Washington President’s Achievement Award for the Graduating Senior with the Highest Academic Achievements
  • 1996 Phi Beta Kappa Honor Society. Invited
  • 1997-2005 Medical Scientist Training Program Scholarship, Mayo Clinic College of Medicine
  • 2001 Best poster award, Department of Pediatrics and Adolescent Medicine, Mayo Clinic Research Symposium
  • 2005-2011 Physician Scientist Training Program Scholarship, Washington University School of Medicine
  • 2008-2011 Mallinckrodt Foundation Post-doctoral Research Fellowship in Medical Oncology
  • 2010 Concept Award, Department of Defense
  • 2011 Young Investigator Award, Conquer Cancer Foundation, ASCO
  • 2013 Cancer Frontier Fund Award, BJH Foundation
  • 2013 Pardee Foundation Scholar Award